Coordinating Center: Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy


The goal of this research is to follow Barrett's Esophagus patients for 3 years using the tethered capsule endomicroscopy device with distal scanning and a compact imaging system in a multi-site clinical study.

Study Start Date

April, 04 2017

Estimated Completion Date

December 2020


  • Device: Tethered Capsule Endomicroscopy (TCE)

Study ID

Massachusetts General Hospital -- 2017P000604



Trial ID


Study Type


Trial Phase


Enrollment Quota



Massachusetts General Hospital

Inclusion Criteria

  • Subjects over the age of 18
  • Subjects who are capable of giving informed consent
  • Subjects with a diagnosis of BE without high grade dysplasia, intramucosal adenocarcinoma or esophageal adenocarcinoma, confirmed by endoscopic biopsy,
  • Subjects who had or will have a standard of care EGD within 15 months
  • Subjects must have no solid food for at least 4 hours prior to the procedure, and only clear liquids for 2 hours prior to the procedure

Exclusion Criteria

  • Subjects with prior endoscopic ablation or resection treatment of BE at enrollment visit
  • Subjects with esophageal fistula and/or esophageal strictures
  • Subjects with the inability to swallow capsules
  • Self reported pregnancy




18 Years and older

Accepts Healthy Volunteers


Study Locations and Contact Information (5)

Study Location Distance Name Phone Email
Massachusetts General Hospital - Boston, Massachusetts 2.8 miles Guillermo Tearney MD 617-724-2979
Columbia University Medical Center - New York, New York 181.2 miles John Poneros MD 212-305-1909
Mayo Clinic Jacksonville - Jacksonville, Florida 1,015.8 miles Michael Wallace MD 904-953-7190
Mayo Clinic Rochester - Rochester, Minnesota 1,083.1 miles Kenneth Wang MD None
VA Clinic - Kansas City, Missouri 1,247.2 miles Prateek Sharma MD 816-921-9311 provides clinical trial listings in an easy to view format. All clinical trial information is pulled directly from This website does not guarantee acceptance into any clinical trial, and is not responsible for adverse events that may be incurred from a clinical trial.