Cognitive Recovery With Cannabis Abstinence Among High School-Aged Adolescents

Description

This study will use a randomized controlled design to test whether 30 days of cannabis abstinence, compared to 30 days of monitoring, is associated with improvements in cognitive functioning. Non-using controls will also be enrolled to determine the clinical significance of any cognitive improvements with abstinence.

Study Start Date

August, 01 2017

Estimated Completion Date

January 2022

Interventions

  • Behavioral: Abstinence

Study ID

Massachusetts General Hospital -- 1K23DA042946

Status

Recruiting

Trial ID

NCT03276221

Study Type

Interventional

Trial Phase

N/A

Enrollment Quota

210

Sponsor

Massachusetts General Hospital

General

Inclusion Criteria

  • Male and female adolescents from the Boston area who are between the ages of 13 and 19 (inclusive)
  • Have a parent or legal guardian who is able and willing to provide written informed consent for the active study phase (if under the age of 18)
  • Competent and willing to provide written informed assent for the active study phase (if under the age of 18)
  • Competent and able to provide written informed consent (if age 18 or older)
  • Able to communicate in English language
  • Able to commit to 9 study visits in approximately 60 days Cannabis-Using Group

    Inclusion Criteria

    • Use of cannabis at least once per week on most weeks
    • Cannabis use reported within 7 days of both baseline visits Non-Using Group

      Inclusion Criteria

      • Use of cannabis less than 5 times in lifetime General

      Exclusion Criteria

      • In the opinion of the investigator, not able to safely participate in this study because of any medical or psychological issues (e.g. psychosis) that might compromise their safety. Non-Using Group

      Exclusion Criteria

      • No cannabis use in the past year
      • No cannabis use before age 16

Gender

All

Ages

13 Years to 19 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Study Locations and Contact Information (4)

Study Location Distance Name Phone Email
Massachusetts General Hospital - Boston, Massachusetts 2.8 miles Randi M Schuster PhD 617-643-6673 Rschuster@mgh.harvard.edu
Massachusetts General Hospital - Boston, Massachusetts 2.8 miles Randi M Schuster PhD 617-643-6673 Rschuster@mgh.harvard.edu
Massachusetts General Hospital - Boston, Massachusetts 2.8 miles Randi M Schuster PhD 617-643-6673 Rschuster@mgh.harvard.edu
Massachusetts General Hospital - Boston, Massachusetts 2.8 miles Randi M Schuster PhD 617-643-6673 Rschuster@mgh.harvard.edu

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