Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome

Description

This study will assess the tolerability and palatability of an amino acid based oral rehydration solution (enterade®) compared to current oral rehydration solution among children with short bowel syndrome .

Study Start Date

August, 16 2017

Estimated Completion Date

October 2017

Interventions

  • Dietary Supplement: Enterade® oral rehydration solution

Study ID

Boston Children’s Hospital -- IRB-P00024854

Status

Recruiting

Trial ID

NCT03105362

Study Type

Interventional

Trial Phase

N/A

Enrollment Quota

5

Sponsor

Boston Children’s Hospital

Inclusion Criteria

  • Male and female patients with a diagnosis of short bowel syndrome (as defined by surgical therapy for congenital or acquired gastrointestinal disease) between the ages of 1-17
  • Patients who are in intestinal continuity or with diverting ileostomy, jejunostomy
  • Patients must be on a stable enteral nutrition regimen with oral rehydration fluids that are taken orally.
  • Stable GI medication regimen (e.g., loperamide, cholestyramine, small bowel bacterial overgrowth (SBBO) regimen)

Exclusion Criteria

  • Patients receiving IV antibiotics within the previous 72h.
  • Patients with a primary diagnosis of a motility disorder (e.g., chronic intestinal pseudo-obstruction) or epithelial cell disorder (e.g., microvillus inclusion disease)
  • Malnourished (as defined by Weight/Height Z-score (WHZ) <-2)

Gender

All

Ages

1 Year to 17 Years

Accepts Healthy Volunteers

No

Study Locations and Contact Information (4)

Study Location Distance Name Phone Email
Boston Childrens Hospital - Boston, Massachusetts 2.6 miles None None None
Boston Childrens Hospital - Boston, Massachusetts 2.6 miles None None None
Boston Childrens Hospital - Boston, Massachusetts 2.6 miles None None None
Boston Childrens Hospital - Boston, Massachusetts 2.6 miles None None None

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