A Study to Test Combination Treatments in People With Advanced Renal Cell Carcinoma

Description

The purpose of this study is to determine whether nivolumab in combination with other therapies is more effective than nivolumab in combination with ipilimumab in treating patients/subjects with advanced renal cell carcinoma.

Study Start Date

January, 17 2017

Estimated Completion Date

January 2022

Interventions

  • Biological: Nivolumab
  • Biological: Relatlimab
  • Biological: Ipilimumab

Study ID

Bristol-Myers Squibb -- CA018-005

Status

Recruiting

Trial ID

NCT02996110

Study Type

Interventional

Trial Phase

Phase 2

Enrollment Quota

200

Sponsor

Bristol-Myers Squibb

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com

Inclusion Criteria

  • Advanced Renal Cell Carcinoma
  • Must have at least 1 lesion with measurable disease
  • Life expectancy of at least 3 months

Exclusion Criteria

  • Patients/subjects with suspected or known central nervous system metastases unless adequately treated
  • Patients/subjects with autoimmune disease
  • Patients/subjects who need daily oxygen therapy Other protocol defined inclusion/exclusion criteria could apply

Gender

All

Ages

18 Years and older

Accepts Healthy Volunteers

No

Study Locations and Contact Information (126)

Study Location Distance Name Phone Email
Dana Farber Cancer Institute - Boston, Massachusetts 2.4 miles Toni Choueiri Site 0001 617-632-4420 None
Dana Farber Cancer Institute - Boston, Massachusetts 2.4 miles Toni Choueiri Site 0001 617-632-4420 None
Dana Farber Cancer Institute - Boston, Massachusetts 2.4 miles Toni Choueiri Site 0001 617-632-4420 None
Dana Farber Cancer Institute - Boston, Massachusetts 2.4 miles Toni Choueiri Site 0001 617-632-4420 None
Dana Farber Cancer Institute - Boston, Massachusetts 2.4 miles Toni Choueiri Site 0001 617-632-4420 None
Dana Farber Cancer Institute - Boston, Massachusetts 2.4 miles Toni Choueiri Site 0001 617-632-4420 None
Yale Cancer Center - New Haven, Connecticut 119.2 miles Harriet Kluger Site 0037 203-500-0834 None
Yale Cancer Center - New Haven, Connecticut 119.2 miles Harriet Kluger Site 0037 203-500-0834 None
Yale Cancer Center - New Haven, Connecticut 119.2 miles Harriet Kluger Site 0037 203-500-0834 None
Yale Cancer Center - New Haven, Connecticut 119.2 miles Harriet Kluger Site 0037 203-500-0834 None
Yale Cancer Center - New Haven, Connecticut 119.2 miles Harriet Kluger Site 0037 203-500-0834 None
Yale Cancer Center - New Haven, Connecticut 119.2 miles Harriet Kluger Site 0037 203-500-0834 None
Memorial Sloan Kettering Cancer Center - New York, New York 187.1 miles ChungHan Lee Site 0005 646-888-1397 None
Memorial Sloan Kettering Cancer Center - New York, New York 187.1 miles ChungHan Lee Site 0005 646-888-1397 None
Memorial Sloan Kettering Cancer Center - New York, New York 187.1 miles ChungHan Lee Site 0005 646-888-1397 None
Memorial Sloan Kettering Cancer Center - New York, New York 187.1 miles ChungHan Lee Site 0005 646-888-1397 None
Memorial Sloan Kettering Cancer Center - New York, New York 187.1 miles ChungHan Lee Site 0005 646-888-1397 None
Memorial Sloan Kettering Cancer Center - New York, New York 187.1 miles ChungHan Lee Site 0005 646-888-1397 None
Lehigh Valley Health Network - Allentown, Pennsylvania 257.9 miles Suresh Nair Site 0002 610-402-1184 None
Lehigh Valley Health Network - Allentown, Pennsylvania 257.9 miles Suresh Nair Site 0002 610-402-1184 None
Lehigh Valley Health Network - Allentown, Pennsylvania 257.9 miles Suresh Nair Site 0002 610-402-1184 None
Lehigh Valley Health Network - Allentown, Pennsylvania 257.9 miles Suresh Nair Site 0002 610-402-1184 None
Lehigh Valley Health Network - Allentown, Pennsylvania 257.9 miles Suresh Nair Site 0002 610-402-1184 None
Lehigh Valley Health Network - Allentown, Pennsylvania 257.9 miles Suresh Nair Site 0002 610-402-1184 None
Sidney Kimmel Cancer Center At Johns Hopkins - Baltimore, Maryland 357.9 miles Michael Carducci Site 0007 410-502-5101 None
Sidney Kimmel Cancer Center At Johns Hopkins - Baltimore, Maryland 357.9 miles Michael Carducci Site 0007 410-502-5101 None
Sidney Kimmel Cancer Center At Johns Hopkins - Baltimore, Maryland 357.9 miles Michael Carducci Site 0007 410-502-5101 None
Sidney Kimmel Cancer Center At Johns Hopkins - Baltimore, Maryland 357.9 miles Michael Carducci Site 0007 410-502-5101 None
Sidney Kimmel Cancer Center At Johns Hopkins - Baltimore, Maryland 357.9 miles Michael Carducci Site 0007 410-502-5101 None
Sidney Kimmel Cancer Center At Johns Hopkins - Baltimore, Maryland 357.9 miles Michael Carducci Site 0007 410-502-5101 None
Roswell Park Cancer Institute - Buffalo, New York 397.2 miles Saby George Site 0004 716-845-7754 None
Roswell Park Cancer Institute - Buffalo, New York 397.2 miles Saby George Site 0004 716-845-7754 None
Roswell Park Cancer Institute - Buffalo, New York 397.2 miles Saby George Site 0004 716-845-7754 None
Roswell Park Cancer Institute - Buffalo, New York 397.2 miles Saby George Site 0004 716-845-7754 None
Roswell Park Cancer Institute - Buffalo, New York 397.2 miles Saby George Site 0004 716-845-7754 None
Roswell Park Cancer Institute - Buffalo, New York 397.2 miles Saby George Site 0004 716-845-7754 None
The Ohio State University - Columbus, Ohio 641.8 miles Thomas Olencki Site 0014 614-293-7833 None
The Ohio State University - Columbus, Ohio 641.8 miles Thomas Olencki Site 0014 614-293-7833 None
The Ohio State University - Columbus, Ohio 641.8 miles Thomas Olencki Site 0014 614-293-7833 None
The Ohio State University - Columbus, Ohio 641.8 miles Thomas Olencki Site 0014 614-293-7833 None
The Ohio State University - Columbus, Ohio 641.8 miles Thomas Olencki Site 0014 614-293-7833 None
The Ohio State University - Columbus, Ohio 641.8 miles Thomas Olencki Site 0014 614-293-7833 None
Rush University Med Ctr - Chicago, Illinois 851.3 miles Timothy Kuzel Site 0006 312-942-8004 None
Rush University Med Ctr - Chicago, Illinois 851.3 miles Timothy Kuzel Site 0006 312-942-8004 None
Rush University Med Ctr - Chicago, Illinois 851.3 miles Timothy Kuzel Site 0006 312-942-8004 None
Rush University Med Ctr - Chicago, Illinois 851.3 miles Timothy Kuzel Site 0006 312-942-8004 None
Rush University Med Ctr - Chicago, Illinois 851.3 miles Timothy Kuzel Site 0006 312-942-8004 None
Rush University Med Ctr - Chicago, Illinois 851.3 miles Timothy Kuzel Site 0006 312-942-8004 None
Augusta University - Augusta, Georgia 855.1 miles Jigarkumar Parikh Site 0031 706-721-1206 None
Augusta University - Augusta, Georgia 855.1 miles Jigarkumar Parikh Site 0031 706-721-1206 None
Augusta University - Augusta, Georgia 855.1 miles Jigarkumar Parikh Site 0031 706-721-1206 None
Augusta University - Augusta, Georgia 855.1 miles Jigarkumar Parikh Site 0031 706-721-1206 None
Augusta University - Augusta, Georgia 855.1 miles Jigarkumar Parikh Site 0031 706-721-1206 None
Augusta University - Augusta, Georgia 855.1 miles Jigarkumar Parikh Site 0031 706-721-1206 None
Washington University School Of Medicine - Saint Louis, Missouri 1,039.5 miles James Hsieh Site 0008 314-747-1343 None
Washington University School Of Medicine - Saint Louis, Missouri 1,039.5 miles James Hsieh Site 0008 314-747-1343 None
Washington University School Of Medicine - Saint Louis, Missouri 1,039.5 miles James Hsieh Site 0008 314-747-1343 None
Washington University School Of Medicine - Saint Louis, Missouri 1,039.5 miles James Hsieh Site 0008 314-747-1343 None
Washington University School Of Medicine - Saint Louis, Missouri 1,039.5 miles James Hsieh Site 0008 314-747-1343 None
Washington University School Of Medicine - Saint Louis, Missouri 1,039.5 miles James Hsieh Site 0008 314-747-1343 None
Seattle Cancer Care Alliance - Seattle, Washington 2,490.2 miles Scott Tykodi Site 0003 206-288-7763 None
Seattle Cancer Care Alliance - Seattle, Washington 2,490.2 miles Scott Tykodi Site 0003 206-288-7763 None
Seattle Cancer Care Alliance - Seattle, Washington 2,490.2 miles Scott Tykodi Site 0003 206-288-7763 None
Seattle Cancer Care Alliance - Seattle, Washington 2,490.2 miles Scott Tykodi Site 0003 206-288-7763 None
Seattle Cancer Care Alliance - Seattle, Washington 2,490.2 miles Scott Tykodi Site 0003 206-288-7763 None
Seattle Cancer Care Alliance - Seattle, Washington 2,490.2 miles Scott Tykodi Site 0003 206-288-7763 None
Local Institution - San Francisco, California 2,698.0 miles Site 0009 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0011 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0033 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0028 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0029 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0035 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0034 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0030 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0023 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0022 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0012 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0015 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0013 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0033 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0028 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0029 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0035 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0034 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0030 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0023 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0012 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0033 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0028 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0029 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0035 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0034 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0030 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0023 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0022 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0012 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0016 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0009 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0011 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0032 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0033 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0028 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0038 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0029 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0035 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0034 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0022 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0012 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0028 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0029 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0035 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0034 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0023 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0022 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0016 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0009 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0011 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0032 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0033 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0028 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0029 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0035 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0034 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0030 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0023 None None
Local Institution - San Francisco, California 2,698.0 miles Site 0022 None None

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