Cutaneous and Systemic Reactions to Metal Implants


The purpose of this study is to evaluate if metal patch testing in metal allergic patients is useful for predicting the development of allergic skin disease or systemic symptoms in patients who recieve a metal orthopedic implant.

Study Start Date

August 2014

Estimated Completion Date

August 2018


  • Other: Patch Test


  • Internal Medicine: Allergy/Immunology,Dermatology,Infectious Disease
  • Infectious Disease: Derm Infectious Disease
  • Family Medicine: Dermatology
  • Allergy/Immunology: Derm Allergy/Immunology
  • Dermatology: Derm Allergy/Immunology,Derm Infectious Disease

MeSH Terms

  • Dermatitis, Allergic Contact
  • Dermatitis, Contact
  • Hypersensitivity
  • Skin Diseases, Eczematous

Study ID

Winthrop University Hospital -- 14318



Trial ID


Study Type


Trial Phase


Enrollment Quota



Winthrop University Hospital

Inclusion Criteria 1. Age ?18 years with a history of metal allergy who require joint repair (hip, knee and/or shoulder) 2. Able to undergo patch testing Exclusion Criteria 1. Patients on oral immunosuppressant medications within 4 weeks of patch testing or topical corticosteroids to the back within 1 week of patch testing 2. Patients who are pregnant or breastfeeding




18 Years and older

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Study Locations and Contact Information (2)

Study Location Distance Name Phone Email
Winthrop University Hospital - Mineola, New York 38.5 miles Marcella R Aquino MD 516-663-2097
University of Cincinnati College of Medicine - Cincinnati, Ohio 612.9 miles Jonathan Bernstein MD 513-558-5533 provides clinical trial listings in an easy to view format. All clinical trial information is pulled directly from This website does not guarantee acceptance into any clinical trial, and is not responsible for adverse events that may be incurred from a clinical trial.