Improving Trans-oral Surgical Outcomes Through Intra-operative Image Guidance

Description

The objective of this research is to perform a pilot study on patients undergoing laryngoscopy for diagnostic and tumor staging purposes (for pharyngeal or laryngeal cancer) in which intraoperative CT imaging will be performed both prior to (but after induction of general endotracheal anesthesia) and during placement of the laryngoscope in order to better understand anatomic changes that occur during instrumentation of the oral cavity and oropharynx. The goals of the study are: 1. Develop a suite of de-identified images and surface renderings that qualitatively show how a tumor and the upper aerodigestive tract anatomy deform during a laryngoscopic evaluation. 2. Create deformation models of the upper aerodigestive tract. This data to be used for future retractor development as well as for virtual image guided surgery.

Study Start Date

April 2015

Estimated Completion Date

July 2018

Interventions

  • Other: Intraoperative CT imaging

Specialties

  • Surgery: Head and Neck,Radiology/Diagnostics,Surgical Oncology
  • Oncology: Diagnostics/Radiology,Head and Neck
  • Radiology: CT/SPECT/PET
  • Otolaryngology: Head and Neck,Radiology/Diagnostics

MeSH Terms

  • Head and Neck Neoplasms
  • Oropharyngeal Neoplasms
  • Otorhinolaryngologic Diseases

Study ID

Dartmouth-Hitchcock Medical Center -- D14189

Status

Unknown

Trial ID

NCT02405000

Study Type

Interventional

Trial Phase

N/A

Enrollment Quota

10

Sponsor

Dartmouth-Hitchcock Medical Center

Inclusion Criteria

  • Adult patients (>18 years) seen in the Head and Neck Tumor Clinic who will require laryngoscopy in the operating room for diagnosis and staging of known or suspected tumors of the upper aerodigestive tract.

Exclusion Criteria

  • Patients who are unable to tolerate general anesthesia.
  • Patients who are felt to be a "difficult airway" for induction of general endotracheal anesthesia.
  • Patients with excessive dental restorations and amalgam.

Gender

Both

Ages

18 Years and older

Accepts Healthy Volunteers

No

Study Locations and Contact Information (1)

Study Location Distance Name Phone Email
Dartmouth Hitchcock Medical Center Norris Cotton Cancer Center - Lebanon, New Hampshire 105.5 miles Joseph Paydarfar None Joseph.A.Paydarfar@hitchcock.org

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