Adult Liver Transplant Enhanced Care
The purpose of this study is to pilot-test a tailored telemetric intervention to improve adherence to medications in adults who had a liver transplant and are presently non-adherent (as measured by tacrolimus levels).
Study Start Date
Estimated Completion Date
- Behavioral: Behavioral Telehealth
- Gastroenterology: Transplant
- Physician Assistant: Gastroenterology
- Behavioral Telehealth
- Liver Transplant Recipients,
Mount Sinai School of Medicine -- GCO 14-1876
Mount Sinai School of Medicine
- The patient is at least 18 years of age.
- The patient received a liver transplant at least 2 years prior to initiation of the research protocol.
- The patient is able to provide consent (i.e. is not encephalopathic or does not have significant cognitive impairment). Consent may be obtained either by phone or in person (following a script) and is documented by the researcher.
- The patient is prescribed tacrolimus (either brand or generic formulation).
- The patient is not receiving Hepatitis C treatment during the intervention (given this can affect levels of tacrolimus and adherence behaviors)
- Thee patient has been seen in the liver transplant clinic at least once in the last two years.
- The patient's MLVI value was ? 2, with at least 3 levels present to make this determination. Only tacrolimus levels drawn in the outpatient setting will be included in SD calculations. Tacrolimus levels in the inpatient setting (i.e. during a hospitalization) will be excluded.
- The patient speaks English or Spanish at a level that allows him/her to understand the study procedures and consent to the study.
- The patient received a liver transplant less than 2 years prior to enrollment.
- The patient received a dual transplant (i.e. liver and kidney).
- The treating physician has instructed the patient not to obtain tacrolimus levels for at least one year in the past year.
- The patient does not understand the study procedures. This will be verified by asking the patient to repeat the study procedures.
- The patient is actively psychotic or severely disoriented due to any cause, including hepatic encephalopathy (temporary exclusion) or severe cognitive impairment.
- The patient is not medically stable or is hospitalized (temporary exclusion until stabilized).
18 Years and older
Accepts Healthy Volunteers
Study Locations and Contact Information (1)
|Icahn School of Medicine at Mount Sinai - New York, New York||46.8 miles||None||None||None|