Manuka Honey for Wound Care


Since antiquity, honey has been recognized for its healing properties. Literature about the use of medicinal honey for wound care dates back centuries with recent data suggesting its use in patients suffering from burns or pressure ulcers. Research has shown Manuka honey (Leptospermum scoparium) to have significant immune benefits and the ability to influence all phases of wound healing: inflammation, proliferation and remodeling. In addition, numerous clinical studies have identified positive benefits for wound healing. However, there is a lack of prospective, randomized controlled data on the use of honey as a medicinal agent in local wound care and scar healing. In order to better understand Manuka Honey's ability to aid in healing, the investigators are conducting a randomized, controlled, single-blinded study of patients undergoing reconstructive surgery. This project uses split thickness skin graft and free tissue transfer donor sites as standard wound models to compare the effects of Manuka Honey versus standard wound care therapies. Through the use of standard wound model and objective measurement tools, the investigators hope to better elucidate any benefits of this novel wound care 'technology.'

Study Start Date

December 2013

Estimated Completion Date

December 2017


  • Drug: Manuka Honey Dressing


  • Internal Medicine: Complementary Medicine,Critical Care/Hospitalist
  • Emergency Medicine: Trauma
  • Physician Assistant: Emergency/Trauma

MeSH Terms

  • Wound Healing

Study ID

Mount Sinai School of Medicine -- GCO 13-1507



Trial ID


Study Type


Trial Phase

Phase 4

Enrollment Quota



Mount Sinai School of Medicine

Inclusion Criteria

  • All patients over the age of 18 undergoing reconstructive surgery with FTT and/or STSG

Exclusion Criteria

  • All patients under the age of 18
  • Any patients with documented honey allergy
  • Patients with documented collagen vascular diseases
  • Patients with documented coagulopathy
  • Patients with history of prior skin grafting




18 Years and older

Accepts Healthy Volunteers


Study Locations and Contact Information (1)

Study Location Distance Name Phone Email
Icahn School of Medicine at Mount Sinai - New York, New York 46.8 miles None None None provides clinical trial listings in an easy to view format. All clinical trial information is pulled directly from This website does not guarantee acceptance into any clinical trial, and is not responsible for adverse events that may be incurred from a clinical trial.