Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-angle Glaucoma or Ocular Hypertension

Description

This study will evaluate the efficacy and safety of bimatoprost sustained-release (SR) in patients with open-angle glaucoma or ocular hypertension. The study includes a 12-month treatment period with an 8-month extended follow-up.

Study Start Date

October 2014

Estimated Completion Date

August 2018

Interventions

  • Drug: Bimatoprost sustained-release
  • Drug: Timolol
  • Other: Sham
  • Drug: Timolol Vehicle (placebo)

Specialties

  • Ophthalmology: Clinical Pharmacology,Glaucoma
  • Physician Assistant: Ophthalmology

MeSH Terms

  • Bimatoprost
  • Glaucoma
  • Glaucoma, Open-Angle
  • Ocular Hypertension

Study ID

Allergan -- 192024-091

Status

Unknown

Trial ID

NCT02247804

Study Type

Interventional

Trial Phase

Phase 3

Enrollment Quota

600

Sponsor

Allergan

Inclusion Criteria

  • Diagnosis of either open-angle glaucoma or ocular hypertension in both eyes that require IOP-lowering treatment

Exclusion Criteria

  • Previous enrollment in Allergan Study 192024-041D
  • Eye surgery (including cataract surgery) and/or any eye laser surgery within the past 6 months in the study eye
  • Anticipated need for laser eye surgery during the study
  • History of glaucoma surgery

Gender

Both

Ages

18 Years and older

Accepts Healthy Volunteers

No

Study Locations and Contact Information (60)

Study Location Distance Name Phone Email
Eyecare Ophthalmology Associates PC - Bethage, New York 35.4 miles None None None
Montefiore Medical Center - Bronx, New York 40.3 miles None None None
Harkness Eye Institute - New York, New York 44.8 miles None None None
Northern New Jersey Eye Institute PA - South Orange, New Jersey 62.0 miles None None None
Glaucoma Consultants of the Capital Region - Slingelands, New York 103.8 miles None None None
Wills Eye Institute Glaucoma Research Center - Philadelphia, Pennsylvania 133.3 miles None None None
MedRACS LLC - Quincy, Massachusetts 139.9 miles None None None
Eyesight Ophthalmic Services PA - Portsmouth, New Hampshire 180.2 miles None None None
The Eye Center of Central PA - Allenwood, Pennsylvania 196.7 miles None None None
Eye Doctors of Washington - Chevy Chase, Maryland 255.3 miles None None None
Rochester Ophthalmological Group PC - Rochester, New York 257.2 miles None None None
See Clearly Vision Group - McLean, Virginia 263.0 miles None None None
Laurel Eye Clinic - Brookville, Pennsylvania 303.1 miles None None None
Virginia Eye Consultants - Norfolk, Virginia 341.7 miles None None None
Associates in Ophthalmology - Pittsburgh, Pennsylvania 356.5 miles None None None
West Virginia University - Morgantown, West Virginia 371.3 miles None None None
Albemarle Clinical Trials LLC - Elizabeth City, North Carolina 377.2 miles None None None
University Hospitals of Cleveland - Cleveland, Ohio 434.6 miles None None None
Glaucoma Center of Michigan - Southfield, Michigan 525.1 miles None None None
University of Michigan - Ann Arbor, Michigan 545.4 miles None None None
Mundorf Eye Center - Charlotte, North Carolina 585.2 miles None None None
Indiana University School of Medicine - Indianapolis, Indiana 686.4 miles None None None
Chicago Eye Specialists - Chicago, Illinois 745.0 miles None None None
University of Illinois at Chicago - Chicago, Illinois 748.9 miles None None None
Chicago Cornea Consultants Ltd - Highland Park, Illinois 754.8 miles None None None
Coastal Research Associates LLC - Roswell, Georgia 784.2 miles None None None
Mayo Clinic Jacksonville - Jacksonville, Florida 886.5 miles None None None
Washington University - St. Louis, Missouri 919.8 miles None None None
Nature Coast Clinical Research - Crystal River, Florida 1,004.8 miles None None None
Minnesota Eye Constultants PA - Bloomington, Minnesota 1,043.4 miles None None None
East Florida Eye Institute - Stuart, Florida 1,049.8 miles None None None
International Research Center - Tampa, Florida 1,055.2 miles None None None
Palm Beach Eye Center INC - Atlantis, Florida 1,084.5 miles None None None
Silverstein Eye Centers - Kansas City, Missouri 1,131.1 miles None None None
University of Arkansas for Medical Sciences - Little Rock, Arkansas 1,131.5 miles None None None
Moyes Eye Center PC - Kansas City, Missouri 1,135.5 miles None None None
Center for Excellence in Eye Care - Miami, Florida 1,152.7 miles None None None
Glaucoma Associates of Texas - Dallas, Texas 1,416.1 miles None None None
Houston Eye Associates - Houston, Texas 1,478.1 miles None None None
Keystone Research LTD - Austin, Texas 1,562.3 miles None None None
R and R Eye Research LLC - San Antonio, Texas 1,633.8 miles None None None
Focal Point Vision - San Antonio, Texas 1,635.9 miles None None None
Medical Center Ophthalmology Associates - San Antonio, Texas 1,637.6 miles None None None
Eye Associates of Colorado Springs - Colorado Springs, Colorado 1,672.5 miles None None None
The Cataract Glaucoma Refractive Surgery Center - El Paso, Texas 1,949.2 miles None None None
Hammond Eye Institute - Logan, Utah 1,984.5 miles None None None
Arizona Glaucoma Specialists - Phoenix, Arizona 2,174.5 miles None None None
West Coast Eye Care Associates - San Diego, California 2,466.9 miles None None None
Hamilton Glaucoma Center Shiley Eye Center UCSD - La Jolla, California 2,474.1 miles None None None
Lakeside Vision Center - Irvine, California 2,476.2 miles None None None
Foothill Eye Institute - Pasadena, California 2,478.1 miles None None None
Montebello Medical Eye Center Inc - Montebello, California 2,483.3 miles None None None
Lugene Eye Institute - Glendale, California 2,486.6 miles None None None
Atlantis Eye Care - Long Beach, California 2,488.7 miles None None None
Glaucoma Institute of Beverly Hills - Los Angeles, California 2,495.4 miles None None None
Drs Fine Hoffman Sims LLC - Eugene, Oregon 2,507.2 miles None None None
Martel Eye Medical Group - Rancho Cordova, California 2,524.3 miles None None None
Grutzmacher Lewis and Sierra Inc - Sacramento, California 2,534.1 miles None None None
Stanford University - Palo Alto, California 2,597.2 miles None None None
Pacific Eye Associates - San Francisco, California 2,604.7 miles None None None

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