Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-angle Glaucoma or Ocular Hypertension

Description

This study will evaluate the efficacy and safety of bimatoprost sustained-release (SR) in patients with open-angle glaucoma or ocular hypertension. The study includes a 12-month treatment period with an 8-month extended follow-up.

Study Start Date

October 2014

Estimated Completion Date

August 2018

Interventions

  • Drug: Bimatoprost sustained-release
  • Drug: Timolol
  • Other: Sham
  • Drug: Timolol Vehicle (placebo)

Specialties

  • Ophthalmology: Clinical Pharmacology,Glaucoma
  • Physician Assistant: Ophthalmology

MeSH Terms

  • Bimatoprost
  • Glaucoma
  • Glaucoma, Open-Angle
  • Ocular Hypertension

Study ID

Allergan -- 192024-091

Status

Unknown

Trial ID

NCT02247804

Study Type

Interventional

Trial Phase

Phase 3

Enrollment Quota

600

Sponsor

Allergan

Inclusion Criteria

  • Diagnosis of either open-angle glaucoma or ocular hypertension in both eyes that require IOP-lowering treatment

Exclusion Criteria

  • Previous enrollment in Allergan Study 192024-041D
  • Eye surgery (including cataract surgery) and/or any eye laser surgery within the past 6 months in the study eye
  • Anticipated need for laser eye surgery during the study
  • History of glaucoma surgery

Gender

Both

Ages

18 Years and older

Accepts Healthy Volunteers

No

Study Locations and Contact Information (60)

Study Location Distance Name Phone Email
MedRACS LLC - Quincy, Massachusetts 4.5 miles None None None
Eyesight Ophthalmic Services PA - Portsmouth, New Hampshire 51.4 miles None None None
Glaucoma Consultants of the Capital Region - Slingelands, New York 142.8 miles None None None
Eyecare Ophthalmology Associates PC - Bethage, New York 167.1 miles None None None
Montefiore Medical Center - Bronx, New York 176.6 miles None None None
Harkness Eye Institute - New York, New York 181.2 miles None None None
Northern New Jersey Eye Institute PA - South Orange, New Jersey 198.2 miles None None None
Wills Eye Institute Glaucoma Research Center - Philadelphia, Pennsylvania 269.5 miles None None None
The Eye Center of Central PA - Allenwood, Pennsylvania 317.8 miles None None None
Rochester Ophthalmological Group PC - Rochester, New York 332.3 miles None None None
Eye Doctors of Washington - Chevy Chase, Maryland 391.7 miles None None None
See Clearly Vision Group - McLean, Virginia 399.4 miles None None None
Laurel Eye Clinic - Brookville, Pennsylvania 419.4 miles None None None
Virginia Eye Consultants - Norfolk, Virginia 468.9 miles None None None
Associates in Ophthalmology - Pittsburgh, Pennsylvania 479.6 miles None None None
West Virginia University - Morgantown, West Virginia 501.0 miles None None None
Albemarle Clinical Trials LLC - Elizabeth City, North Carolina 502.2 miles None None None
University Hospitals of Cleveland - Cleveland, Ohio 544.0 miles None None None
Glaucoma Center of Michigan - Southfield, Michigan 622.9 miles None None None
University of Michigan - Ann Arbor, Michigan 645.2 miles None None None
Mundorf Eye Center - Charlotte, North Carolina 720.9 miles None None None
Indiana University School of Medicine - Indianapolis, Indiana 805.0 miles None None None
Chicago Eye Specialists - Chicago, Illinois 848.5 miles None None None
University of Illinois at Chicago - Chicago, Illinois 851.3 miles None None None
Chicago Cornea Consultants Ltd - Highland Park, Illinois 854.8 miles None None None
Coastal Research Associates LLC - Roswell, Georgia 920.6 miles None None None
Mayo Clinic Jacksonville - Jacksonville, Florida 1,015.8 miles None None None
Washington University - St. Louis, Missouri 1,039.5 miles None None None
Minnesota Eye Constultants PA - Bloomington, Minnesota 1,123.6 miles None None None
Nature Coast Clinical Research - Crystal River, Florida 1,134.5 miles None None None
East Florida Eye Institute - Stuart, Florida 1,170.8 miles None None None
International Research Center - Tampa, Florida 1,183.5 miles None None None
Palm Beach Eye Center INC - Atlantis, Florida 1,204.0 miles None None None
Silverstein Eye Centers - Kansas City, Missouri 1,244.5 miles None None None
Moyes Eye Center PC - Kansas City, Missouri 1,247.6 miles None None None
University of Arkansas for Medical Sciences - Little Rock, Arkansas 1,261.1 miles None None None
Center for Excellence in Eye Care - Miami, Florida 1,271.8 miles None None None
Glaucoma Associates of Texas - Dallas, Texas 1,545.0 miles None None None
Houston Eye Associates - Houston, Texas 1,612.3 miles None None None
Keystone Research LTD - Austin, Texas 1,694.2 miles None None None
R and R Eye Research LLC - San Antonio, Texas 1,766.2 miles None None None
Focal Point Vision - San Antonio, Texas 1,768.2 miles None None None
Medical Center Ophthalmology Associates - San Antonio, Texas 1,769.8 miles None None None
Eye Associates of Colorado Springs - Colorado Springs, Colorado 1,777.2 miles None None None
The Cataract Glaucoma Refractive Surgery Center - El Paso, Texas 2,071.1 miles None None None
Hammond Eye Institute - Logan, Utah 2,073.8 miles None None None
Arizona Glaucoma Specialists - Phoenix, Arizona 2,287.2 miles None None None
West Coast Eye Care Associates - San Diego, California 2,577.0 miles None None None
Drs Fine Hoffman Sims LLC - Eugene, Oregon 2,581.7 miles None None None
Lakeside Vision Center - Irvine, California 2,583.6 miles None None None
Hamilton Glaucoma Center Shiley Eye Center UCSD - La Jolla, California 2,583.7 miles None None None
Foothill Eye Institute - Pasadena, California 2,584.2 miles None None None
Montebello Medical Eye Center Inc - Montebello, California 2,589.7 miles None None None
Lugene Eye Institute - Glendale, California 2,592.6 miles None None None
Atlantis Eye Care - Long Beach, California 2,595.4 miles None None None
Glaucoma Institute of Beverly Hills - Los Angeles, California 2,601.4 miles None None None
Martel Eye Medical Group - Rancho Cordova, California 2,616.5 miles None None None
Grutzmacher Lewis and Sierra Inc - Sacramento, California 2,626.1 miles None None None
Stanford University - Palo Alto, California 2,691.7 miles None None None
Pacific Eye Associates - San Francisco, California 2,698.0 miles None None None

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