Interactive, Health Literacy Promoting Text Messages and HPV Vaccine Completion In Minority Adolescents


Emerging communication technologies, such as text messaging offer low-cost, scalable opportunities to improve health literacy and promote healthy behaviors, such as vaccination. While the investigators reported the success of text message vaccine reminders, effects were limited by their untailored approach. The trans-theoretical model of behavior change supports tailoring interventions to an individual's stage of decision-making. Human papillomavirus (HPV) is the most prevalent sexually transmitted virus in the U.S. and can lead to genital warts, and cervical, anal and penile cancer. The three-dose vaccine is 90-100% efficacious. Minorities are at greatest risk for such cancers but have low HPV vaccine completion rates. Limited health literacy regarding the vaccine can affect series completion. The investigators will compare the effects of enhancing text message vaccination reminders with interactive, vaccine health literacy-promoting information tailored to vaccine decision making-stage on HPV vaccine series completion. The effects of these messages represent a new paradigm in interactive health communications.

Study Start Date

December 2014

Estimated Completion Date

June 2018


  • Behavioral: Enhanced text message reminders
  • Behavioral: Conventional text message reminder


  • Nursing: Education/Training,Telehealth/E-Health
  • Infectious Disease: Vaccine/Immunotherapy

MeSH Terms

  • Human Papillomavirus

Study ID

Columbia University -- IRB-AAAM3960



Trial ID


Study Type


Trial Phase


Enrollment Quota



Columbia University

Inclusion Criteria

  • Parenting adult of adolescent age 11-17 years
  • Adolescent received 1st dose of HPV at a study site within the last 2 weeks.
  • Eligible parent's cell phone has text message capability

Exclusion Criteria

  • Language other than English or Spanish only
  • Parent already in the study
  • Intends to move away from the New York City area in <12 months





Accepts Healthy Volunteers


Study Locations and Contact Information (1)

Study Location Distance Name Phone Email
Columbia University Medical Center - New York, New York 44.8 miles Melissa Stockwell MD MPH 212-342-5732 provides clinical trial listings in an easy to view format. All clinical trial information is pulled directly from This website does not guarantee acceptance into any clinical trial, and is not responsible for adverse events that may be incurred from a clinical trial.