Basic Research Study to Examine the Relation Between Muscle Insulin Resistance and Lipid Production in the Liver.

Description

The purpose of this study is to examine the pathophysiology of insulin resistance and the relation to the metabolic syndrome in humans.

Study Start Date

November 2007

Estimated Completion Date

December 2019

Interventions

  • Other: Exercise Training

Specialties

  • Gastroenterology: Hepatology
  • Physician Assistant: Gastroenterology

MeSH Terms

  • Exercise Training
  • Insulin Resistance

Study ID

Yale University -- 71000-3207

Status

Unknown

Trial ID

NCT02196051

Study Type

Interventional

Trial Phase

N/A

Enrollment Quota

80

Sponsor

Yale University

Inclusion Criteria

  • Body Mass Index < 29 kg/m2
  • No regular exercise routine
  • Non-smokers
  • Absence of systemic and organ disease.

Exclusion Criteria

  • Hematocrit < 35 vol%
  • History of claustrophobia
  • Ferromagnetic implants
  • Regular exercise regimen
  • Not weight stable
  • Any significant hematological, neurological, musculoskeletal or endocrine disease (including diabetes mellitus)
  • Any significant cardiovascular condition, including confirmed CAD and prior cardiovascular events
  • Taking coumadin as anticoagulant therapy.

Gender

Both

Ages

18 Years to 90 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Study Locations and Contact Information (1)

Study Location Distance Name Phone Email
YCCIYNNH Hospital Research Unit - New Haven, Connecticut 18.1 miles Kitt Petersen MD 203-688-4106 kitt.petersen@yale.edu

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