Neuroimaging Effects of Cognitive Behavioral Therapy in Fibromyalgia


This is a brain imaging study of pain responses. The study includes 2-7 visits, lasting from 1-2 hours each. You may be eligible if you are over 18 years old, are either generally healthy or have fibromyalgia, do not have a serious heart condition or certain other medical conditions, are not taking certain types of medications, and are not pregnant.The research takes place at the Brigham & Women's Pain Management Center, 850 Boylston St, Chestnut Hill, and at the MGH Martinos Center for Biomedical Imaging. For further information, please contact the study coordinator Chrissie Cahalan at 617-732-9014 or by email at

Study Start Date

May 2014

Estimated Completion Date

April 2019


  • Behavioral: Education
  • Behavioral: Cognitive Behavioral Therapy


  • Internal Medicine: Rheumatology
  • Rheumatology: Chr Fatigue/Fibromyalgia
  • Physician Assistant: Rheumatology

MeSH Terms

  • Fibromyalgia
  • Myofascial Pain Syndromes

Study ID

Brigham and Women's Hospital -- 2009p001021



Trial ID


Study Type


Trial Phase


Enrollment Quota



Brigham and Women's Hospital

Inclusion Criteria

  • Age 18 or older
  • Meet ACR criteria for RA or FM or be free from chronic pain and rheumatic disease
  • Score on the Pain Catastrophizing Scale in either the top or bottom third of the normative distribution

Exclusion Criteria

  • History of anxiety disorders or significant anxiety symptoms interfering with fMRI procedures (e.g., panic)
  • History of cardiac events
  • History of significant head injury
  • Peripheral neuropathy
  • Use of certain centrally-acting analgesic medications other than over-the-counter preparations (which will be withdrawn for 24 hours prior to testing) or use of recreational drugs
  • Implanted medical or metallic objects
  • Pregnancy
  • Cardiac or nervous system disease




18 Years to 70 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Study Locations and Contact Information (3)

Study Location Distance Name Phone Email
Massaschusetts General Hospital - Charlestown, Massachusetts 2.9 miles Katerina Protsenko BS BA None
Massaschusetts General Hospital - Charlestown, Massachusetts 2.9 miles None None None
Brigham and Womens Hospital - Chestnut Hill, Massachusetts 4.7 miles None None None provides clinical trial listings in an easy to view format. All clinical trial information is pulled directly from This website does not guarantee acceptance into any clinical trial, and is not responsible for adverse events that may be incurred from a clinical trial.