Dominantly Inherited Alzheimer Network (DIAN)

Description

The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.

Study Start Date

January 2009

Estimated Completion Date

June 2019

Interventions

No interventions cited

Specialties

  • Internal Medicine: Neurology
  • Nursing: Neurology
  • Neurology: Dementia
  • Physician Assistant: Neurology

MeSH Terms

  • Alzheimer Disease

Study ID

Washington University School of Medicine -- IA0147

Status

Unknown

Trial ID

NCT00869817

Study Type

Observational

Trial Phase

N/A

Enrollment Quota

400

Sponsor

Washington University School of Medicine

Inclusion Criteria

  • Age 18 or older
  • Child of an individual with a known mutation in a pedigree with autosomal dominant Alzheimer's disease
  • Cognitively normal, or if demented, does not require nursing home level care
  • Fluent in English or Spanish at the 6th grade level
  • Has someone who is not a child of the affected parent who can serve as an informant for the study

Exclusion Criteria

  • Under age 18
  • Medical or psychiatric illness that would interfere in completing initial and follow-up visits
  • Requires nursing home level care
  • Has no one who can serve as a study informant

Gender

Both

Ages

18 Years and older

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Study Locations and Contact Information (11)

Study Location Distance Name Phone Email
Brigham and Womens Hospital - Boston, Massachusetts 2.6 miles None None None
Butler Hospital - Providence, Rhode Island 39.6 miles None None None
Columbia University - New York, New York 181.2 miles None None None
University of Pittsburgh - Pittsburgh, Pennsylvania 478.1 miles None None None
Indiana UniversityIndiana Alzheimer Disease Center - Indianapolis, Indiana 805.0 miles Christina Brown BS CCRC 317-963-7426 chbrown@iupui.edu
Indiana UniversityIndiana Alzheimer Disease Center - Indianapolis, Indiana 805.0 miles None None None
Mayo Clinic Jacksonville - Jacksonville, Florida 1,015.8 miles None None None
Mayo Clinic Jacksonville - Jacksonville, Florida 1,015.8 miles Sochenda Chea BHA CRC 904-953-3234 chea.sochenda@mayo.edu
Washington University School of Medicine - St. Louis, Missouri 1,038.5 miles None None None
Washington University School of Medicine - St. Louis, Missouri 1,038.5 miles Wendy Sigurdson RN MPH 314-362-2256 sigurdsonw@neuro.wustl.edu
University of California San Diego - La Jolla, California 2,583.7 miles None None None

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