Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma

Description

The purpose of this study is to study normal and sarcoma cells. To study these cells we need to have human tissue. You will be having or have already had a procedure to remove tissue. We would like to use some of this tissue. We will use it for laboratory studies on the diagnosis,behavior and treatment of sarcoma. We will perform an extensive biochemical and molecular analysis of your tissue. We will only use extra tissue left over after all needed testing has been done. We will also take blood samples before and/or after your procedure to measure biochemical factors that may help us predict the behavior of sarcoma.

Study Start Date

June 2002

Estimated Completion Date

June 2017

Interventions

  • Other: Specimen protocol

Specialties

  • Oncology: Diagnostics/Radiology,Soft Tissue/Sarcoma
  • Physician Assistant: Hematology/Oncology

MeSH Terms

  • Sarcoma
  • Soft Tissue Sarcoma

Study ID

Memorial Sloan-Kettering Cancer Center -- 02-060

Status

Unknown

Trial ID

NCT00579566

Study Type

Observational

Trial Phase

N/A

Enrollment Quota

3000

Sponsor

Memorial Sloan-Kettering Cancer Center

Inclusion Criteria

  • All patients with known or suspected sarcoma who will have or have had tissue removed for therapeutic or diagnostic purposes.
  • Patients will be entered without preference for any particular racial/ethnic group or gender.
  • Patients may have received prior hormonal therapy, cytotoxic chemotherapy, irradiation, immunotherapy or surgical therapy.
  • Tissue specimens must be large enough in quantity to allow routine pathologic analysis, with the research laboratory specimen removed from the residual specimen, which would otherwise be discarded. Optimal tissue amounts for snap freeze: Core biopsy
  • 2 tissue cores Incisional biopsy
  • 0.5 to 1.5 grams Resected sarcoma specimen
  • 1.0 to 50 grams depending on size of specimen Normal fat or muscle tissue - 0.5 to 4.0 grams (if available from resected sarcoma specimen) Optimal tissue amounts for RNA later Core biopsy
  • 2 tissue cores Incisional biopsy
  • 30 mg (three 3 x 3 x 3 mm cubes) Resected sarcoma specimen
  • 30 mg (three 3 x 3 x 3 mm cubes) Normal fat or muscle tissue
  • 30 mg (three 3 x 3 x 3 mm cube

Exclusion Criteria

  • None

Gender

Both

Ages

N/A

Accepts Healthy Volunteers

No

Study Locations and Contact Information (4)

Study Location Distance Name Phone Email
Memorial Sloan Kettering Cancer Center Suffolk - Commack, New York 26.2 miles None None None
Memorial Sloan Kettering West Harrison - West Harrison, New York 28.7 miles None None None
Memoral Sloan Kettering Cancer Center at Phelps - Sleepy Hollow, New York 33.0 miles None None None
Memorial Sloan Kettering Cancer Center - new York, New York 50.7 miles None None None

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